Skip to main content

GLP-1 Science.

What the trials actually show about these drugs: the weight loss, the side effects, and what helps. Written plainly, cited properly, updated as the evidence moves.

The Nausea Has a Shape

The most common reason people stop a GLP-1 is also the most predictable. It tracks the dose, peaks during the climb, and settles. Knowing the shape is most of managing it.

Why the Brush Has More Hair Than the Floor

Hair shedding on a GLP-1 is real, common, and almost always brushed off as temporary. The biology is more specific than that, and so is what to do about it.

Ozempic Face: What It Is and What Actually Helps

Ozempic face is the gaunt, lined, deflated look that can follow rapid GLP-1 weight loss. What causes it, what a topical can and cannot do, and how to support the skin.

How Much Protein You Actually Need on a GLP-1

The standard 0.8 g/kg guideline was set for people who aren't in a deficit. On a GLP-1, the target to preserve muscle is meaningfully higher. Here are the numbers.

GLP-1 and Muscle Loss: Why It Happens and What Helps

Up to forty percent of the weight lost on a GLP-1 is lean mass, not fat. Why it happens, why it matters more after fifty, and what actually protects muscle.

How Much Weight, and Which Drug

The weight-loss numbers are not the same across these drugs. What each one delivered in its pivotal trial, charted, and why the differences matter less than the marketing.

The Cravings They Did Not Expect to Quiet

Alcohol. Nicotine. Gambling. The trials testing GLP-1s for addictions outside of food are no longer fringe. Here is what they actually show.

Plant vs. Whey Protein for Preserving Muscle

Whey has the reputation, but a head-to-head trial found pea protein built muscle just as well, and for GLP-1 users plant protein has practical advantages too.

The GLP-1 That Skips the Muscle

A third of the weight people lose on a GLP-1 is lean mass. The next generation of these drugs is being engineered around that number.

New evidence, explained plainly.

One email when something worth knowing publishes. No schedule, no filler.