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The GLP-1 era needs better side-effect care.

Aplomb helps women care for their face, hair, muscle, and stomach while the medicine does its job.

  • Four focused products for four common concerns
  • No prescription or appointment required
  • Clear claims with the boundaries left intact
  • 30-day money-back guarantee

Side effects should not become the price of progress.

Women were finally getting access to a medicine that could change their health, then finding themselves on their own with nausea, hair shedding, muscle loss, and fast changes to their face.

Aplomb was built to make the next step calmer, clearer, and easier to act on.

Zachary Poll, founder of APLOMB
Zachary Poll, MSt Founder · Clinical researcher · Healthcare executive and investor
APLOMB founder Zachary Poll looking directly at the camera in the studio
Founder story

Why I started Aplomb.

A short note from founder Zachary Poll on the gap he kept seeing in women’s health.

Developed by employees and graduates of

University of Cambridge
University of Pennsylvania
Children's Hospital of Philadelphia
University of Chicago Medicine

Care should feel clear.

That standard shapes the claims, the products, and the way Aplomb talks about a health experience that can already feel overwhelming.

Every product earns its place.

Every product has a specific job. If a product cannot responsibly claim something, Aplomb leaves it out.

Evidence with boundaries.

We show where evidence is direct, where it is adjacent, and where the product claim ends.

Routine over panic.

The next step should be calm and legible, especially when the purchase sits close to your health.

Built around the concern.

A 36-year-old and a 58-year-old can feel the same side effect. The routine follows what you notice.

Keep feeling like yourself.

Start with the side effect that is changing your day and build only the support you need.

Find your routine