Frequently asked.
Everything we get asked, answered. If yours isn’t here, write us at contact.
No. Facial Serum is a topical cosmetic. Protein, Roots, and Calm are dietary supplements. None require a prescription.
No supplement or topical cosmetic is FDA-approved, that is a category that applies to drugs only. Protein, Roots, and Calm are dietary supplements; their statements have not been evaluated by the FDA. Facial Serum is regulated as a cosmetic.
Yes. The line is designed to work together. Protein, Roots, and Calm each target a specific side-effect pattern. Facial Serum is topical and does not interact with the supplements.
Subscribers save 10-15 percent on every product. Bundling all four in a single subscription order saves an additional small amount on shipping; the live site shows the running total in your bag.
No. Hollow cheeks come from subcutaneous fat-pad loss, which sits below the skin layer that any topical can reach. For volume restoration, the right call is a conversation with a board-certified dermatologist or facial plastic surgeon about HA fillers, Sculptra, or fat grafting. Facial Serum is for the other half of GLP-1 facial change, the dermal thinning that makes skin look crepey and accentuates the hollows.
Cosmeceutical trials of these peptides measure changes at 8 to 12 weeks of consistent twice-daily use. Skin texture and fine-line depth tend to shift first; deeper density changes take the full 12 weeks.
No, and you should be skeptical of any topical brand that claims there is. The peptide actives in the Facial Serum have evidence in general dermal-aging populations (Sederma trials, Li 2023). We extrapolate to the GLP-1 cohort because the underlying biology, collagen loss from metabolic and nutritional stress, is mechanistically the same.
Yes, but on alternating evenings rather than layered. Peptides and retinoids both act on collagen but through different pathways; layering can increase irritation without proportional benefit.
Biotin is in our hair-and-nail consideration set and we have intentionally kept it out of any product where lab-assay interference would be a concern. Biotin above 2.5 mg per day affects roughly 59 percent of common immunoassays, which matters for users monitored for thyroid function during weight loss.
As soon as you can. The best time is when you start your GLP-1, ideally month 1 or 2, before the dose-escalation window for Calm and before dermal change for the Facial Serum begins. If you are already on a GLP-1, start now, the sooner the better. The peptide actives in the Facial Serum measure their effect over an 8 to 12 week window, so earlier starts compound.
Yes. None of the actives are known to interact pharmacologically with GLP-1 receptor agonists. As with any supplement, discuss with your prescriber if you are pregnant, nursing, or under medical care.
Roots stays useful through the recovery window: most people’s hair follicles take six to twelve months to fully reset. Calm ramps down naturally as the gastric-stasis side effect resolves; Protein stays useful for as long as you are losing or maintaining weight.
No. None of the actives interfere with GLP-1 receptor signaling, satiety, or gastric emptying meaningfully. Calm specifically supports the GI window without changing titration.
All products ship in 48 hours from order. US domestic ground delivery. International shipping is rolling out region by region.
15 days, on every product, opened or unopened. We refund the product cost; you cover return shipping unless the product arrived damaged.
Yes, any time, from your account page. Cancellation takes effect immediately for the next renewal.
Each product page has a citations section linking to the relevant studies. The full Evidence page lists everything we cite, organized by product. The Biology page expands each mechanism into long-form.
Facial Serum is manufactured in Australia (the cosmetic-peptide formulation specialty market). Protein, Roots, and Calm are manufactured in GMP-certified US facilities. All three supplements are third-party tested.
The actives in each product are chosen against the strongest published evidence for the specific GLP-1 side effect, not against general-purpose ‘women’s wellness’ criteria. We deliberately leave out ingredients that have no RCT support in the relevant pattern (biotin in Roots is the clearest example).